专利内容由知识产权出版社提供
专利名称：NUCLEIC ACID SEQUENCE FOR
POTENTIATING THE EXPRESSION OFUSEFUL GENE AND METHOD THEREFOR
发明人：YAMADA, Osamu,YOSHIDA, Hiroshi,ZHANG,
Jing
申请号：EP99929745.0申请日：19990708公开号：EP1108780A1公开日：20010620
专利附图：
摘要：Nucleic acid sequences for enhancing expression of a useful gene, which can
increase the production of the gene product by enhancing gene expression, comprising a5'-untranslated region of a viral gene or a fragment or a variant thereof, vectorscomprising the nucleic acid sequence, host cells transformed or transfected with thevector, and methods for enhancing expression of a useful gene with the vector areprovided. In addition, the sequences of the present invention can be utilized for screeningan agent that interacts with IRES elements, and of an IRES-dependent translation initiator,as well as for treating diseases resulting from reduction of cap-dependent mRNAtranslation or reduction of IRES activity, and for determining severity of hepatitis C.
申请人：FUSO PHARMACEUTICAL INDUSTRIES LTD.
地址：7-10, Doshomachi 1-chome, Chuo-ku Osaka-shi, Osaka 541-0045 JP
国籍：JP
代理机构：Gardner, Rebecca
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