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专利名称：PREPARATION OF LIPOSOMES AND
DERIVATIVES
发明人：CHERYL V. GROOM,PETER
TIMMINS,NICOLAS I. PAYNE,FRANKRIDGWAY
申请号：AU2427484申请日：19840208公开号：AU576313B2公开日：19880825
摘要：A method is provided for preparing a stable liposome precursors in the form ofa particulate carrier materials coated with thin films of liposome components, whichmethod includes the steps of dissolving at least one liposome-forming amphipathic lipid,optionally, at least one biologically active compound, and, optionally, at least oneadjuvant in a suitable solvent and employing the resulting solution to coat a suitableparticulate carrier material which is substantially insoluble in the above-mentionedsolvent, to form thin films of liposome components thereon. Upon exposing the coatedcarrier material to water, the thin films of liposome components hydrate. If the carriermaterial is water-insoluble, it is then separated e.g. by filtration or centrifuging.
申请人：E.R. SQUIBB & SONS, INC.
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