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Neisseria meningitidis serogroup B Glycoconjugates

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专利名称:Neisseria meningitidis serogroup B

Glycoconjugates

发明人:Robert Seid申请号:US008262申请日:19970807公开号:US06638513B2公开日:20031028

摘要:The present invention pertains generally to serogroup B glycoconjugates. Moreparticularly, the invention pertains to glycoconjugates formed from a serogroup Bcapsular oligosaccharide derivative (MenB OS derivative) in which sialic acid residue N-acetyl groups are replaced with N-acyl groups. The invention also pertains to vaccineformulations containing the glycoconjugates, methods of making the vaccineformulations, and methods of using the vaccine formulations to treat or preventserogroup B or K1 disease in a mammalian subject.

申请人:CHIRON S.R.L.

代理人:Roberta L. Robins,Alisa A. Harbin,Robert P. Blackburn

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