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专利名称：Identification of novel factors that block
programmed cell death or apoptosis bytargeting JNK
发明人：Guido Franzoso,Salvatore Papa,Concetta
Bubici,Francesca Zazzeroni
申请号：US11000365申请日：20041129公开号：US073218B2公开日：20080205
摘要：Methods and compositions for modulating apoptosis by acting on the c-Jun-N-terminal kinase (JNK) pathway and assays for the isolation of agents capable of
modulating apoptosis, including modulators of the JNK pathway are disclosed. A methodof modulating JNK pathway independent of Gadd46β is disclosed. Methods andcompositions are presented for the preparation and use of novel therapeuticcompositions for modulating diseases and conditions associated with elevated ordecreased apoptosis.
申请人：Guido Franzoso,Salvatore Papa,Concetta Bubici,Francesca Zazzeroni
地址：Chicago IL US,Chicago IL US,Chicago IL US,Chicago IL US
国籍：US,US,US,US
代理机构：Barnes & Thornburg LLP
代理人：Alice O. Martin
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